SCHEMBL10475552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3579374	0.84	POLB (1.00)	POLBL3MBTL1ALDH1A1TDP1CASP3
	SCHEMBL19329397	0.82	POLB (0.64)	POLBL3MBTL1ALDH1A1TDP1CASP3
	SCHEMBL14740993	0.79	POLB (0.63)	POLBL3MBTL1ALDH1A1TDP1CASP3
	SCHEMBL14661066	0.78	NUDT1 (0.52)	POLBL3MBTL1ALDH1A1TSHRKMT2A
	SCHEMBL4132618	0.78	ALDH1A1 (0.64)	POLBL3MBTL1ALDH1A1TDP1CASP3
	SCHEMBL24308561	0.77	ALDH1A1 (0.63)	POLBL3MBTL1ALDH1A1TDP1CASP3
	SCHEMBL27957250	0.77	POLB (0.56)	POLBL3MBTL1ALDH1A1TDP1CASP3
	SCHEMBL30658108	0.77	EGLN1 (0.56)	POLBL3MBTL1ALDH1A1TDP1CASP3
	SCHEMBL27976971	0.77	POLB (0.59)	POLBL3MBTL1ALDH1A1TDP1CASP3
	SCHEMBL25120653	0.76	POLB (0.56)	POLBL3MBTL1ALDH1A1TDP1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.