Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10475638 | 0.96 | CACNA1F (0.50) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7268117 | 0.93 | IDO1 (0.47) | CACNA1BCYP3A4 | |
| SCHEMBL7275109 | 0.90 | ADORA3 (0.59) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL8781999 | 0.89 | IDO1 (0.43) | CACNA1BCYP3A4 | |
| SCHEMBL8782178 | 0.87 | CACNA1B (0.42) | CACNA1B | |
| SCHEMBL30357940 | 0.85 | CACNA1F (0.54) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7269131 | 0.85 | CACNA1F (0.54) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL8928204 | 0.83 | CACNA1C (0.40) | CACNA1BCACNA1CPDE1CMAPTLMNA | |
| SCHEMBL10374259 | 0.80 | CYP2C9 (0.42) | ADORA3CACNA1BCACNA1CPDE1CHIF1A | |
| SCHEMBL10374261 | 0.80 | CACNA1B (0.43) | ADORA3CACNA1BCACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990006923-A1 | IMIDAZOLYL AND PYRIDYL DERIVATIVES OF PHENYL SUBSTITUTED 1,4-DIHYDRO-PYRIDINES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-06-28 | — | — | WO | claimed |