Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 9/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 9/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 9/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 9/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30357940 | 1.00 | CACNA1F (0.54) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7275109 | 0.96 | ADORA3 (0.59) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7277695 | 0.91 | CACNA1C (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL8928277 | 0.91 | CACNA1C (0.54) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10475638 | 0.89 | CACNA1F (0.50) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7268117 | 0.85 | IDO1 (0.47) | CYP3A4 | |
| SCHEMBL10475641 | 0.85 | ADORA3 (0.47) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL8781999 | 0.82 | IDO1 (0.43) | CYP3A4 | |
| SCHEMBL8782178 | 0.81 | CACNA1B (0.42) | — | |
| SCHEMBL10374451 | 0.81 | CACNA1B (0.42) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514693-A | THROMBOXANE A2 SYNTHETASE INHIBITOR, CALCIUM ANTAGONIST | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-05-07 | — | — | US | claimed |
| EP-0373645-B1 | Imidazolyl and pyridyl derivatives of phenyl substituted 1,4 -dihyropyridines and process for their preparation | PHARMACIA SPA (IT) | 1995-04-19 | — | — | EP | claimed |
| EP-0403627-A1 | IMIDAZOLYL AND PYRIDYL DERIVATIVES OF PHENYL SUBSTITUTED 1,4-DIHYDRO-PYRIDINES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-12-27 | — | — | EP | claimed |
| WO-1990006923-A1 | IMIDAZOLYL AND PYRIDYL DERIVATIVES OF PHENYL SUBSTITUTED 1,4-DIHYDRO-PYRIDINES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-06-28 | — | — | WO | claimed |
| EP-0373645-A1 | Imidazolyl and pyridyl derivatives of phenyl substituted 1,4 -dihyropyridines and process for their preparation | PHARMACIA S.p.A. (IT) | 1990-06-20 | — | — | EP | claimed |
| EP-0373645-B1 | Imidazolyl and pyridyl derivatives of phenyl substituted 1,4 -dihyropyridines and process for their preparation | PHARMACIA SPA (IT) | 1995-04-19 | — | — | EP | disclosed |
| EP-0403627-A1 | IMIDAZOLYL AND PYRIDYL DERIVATIVES OF PHENYL SUBSTITUTED 1,4-DIHYDRO-PYRIDINES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-12-27 | — | — | EP | disclosed |
| WO-1990006923-A1 | IMIDAZOLYL AND PYRIDYL DERIVATIVES OF PHENYL SUBSTITUTED 1,4-DIHYDRO-PYRIDINES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-06-28 | — | — | WO | disclosed |
| EP-0373645-A1 | Imidazolyl and pyridyl derivatives of phenyl substituted 1,4 -dihyropyridines and process for their preparation | PHARMACIA S.p.A. (IT) | 1990-06-20 | — | — | EP | disclosed |