Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ADH5 | P11766 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860432 | 0.90 | POLB (0.49) | POLBMAPK1SMN1; SMN2PDE2APDE1A | |
| SCHEMBL7268117 | 0.90 | IDO1 (0.47) | IDO1ADH5CACNA1BPDE4APDE4B | |
| Hydrochloric Acid SCHEMBL8928281 | 0.88 | POLB (0.48) | POLBMAPK1SMN1; SMN2PDE2APDE1A | |
| SCHEMBL8928277 | 0.88 | CACNA1C (0.54) | CACNA1CALDH1A1MAPT | |
| SCHEMBL8928241 | 0.87 | KDM4E (0.53) | CACNA1CGAALMNAALDH1A1HSD17B10 | |
| SCHEMBL8781999 | 0.85 | IDO1 (0.43) | IDO1ADH5CACNA1BPDE4APDE4B | |
| SCHEMBL10475641 | 0.83 | ADORA3 (0.47) | CACNA1CPOLBMAPK1PDE1CLMNA | |
| SCHEMBL8782178 | 0.78 | CACNA1B (0.42) | IDO1CACNA1BPDE4APDE4BPDE4C | |
| SCHEMBL10475638 | 0.78 | CACNA1F (0.50) | CACNA1CPOLBMAPK1SMN1; SMN2PDE1C | |
| SCHEMBL7273476 | 0.77 | CACNA1F (0.53) | CACNA1CPOLBMAPK1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755931-A1 | Dihydropyridine and pyridine derivatives and process for their preparation | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-01-29 | — | — | EP | disclosed |