Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706028 | 0.85 | ITGB1 (0.47) | MTNR1AEHMT2P2RX7MTNR1B | |
| SCHEMBL20193827 | 0.85 | HCRTR1 (0.46) | MTNR1AEHMT2P2RX7 | |
| SCHEMBL10474630 | 0.83 | MTNR1A (0.45) | MTNR1AP2RX7 | |
| SCHEMBL16509689 | 0.82 | MTNR1A (0.47) | MTNR1AEHMT2 | |
| SCHEMBL30829326 | 0.82 | HCRTR1 (0.47) | MTNR1AEHMT2P2RX7MTNR1B | |
| SCHEMBL7275111 | 0.82 | HCRTR1 (0.47) | MTNR1AEHMT2P2RX7MTNR1B | |
| SCHEMBL7275104 | 0.82 | HCRTR1 (0.47) | MTNR1AEHMT2P2RX7MTNR1B | |
| SCHEMBL6703838 | 0.80 | TP53 (0.46) | MTNR1AEHMT2P2RX7MTNR1B | |
| SCHEMBL10474764 | 0.80 | P2RX7 (0.44) | MTNR1AP2RX7MTNR1B | |
| SCHEMBL10785525 | 0.80 | MEN1 (0.46) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990012787-A1 | ENANTIOMER-PURE 5-OXO-2-PYRROLIDINE-PROPANE ACIDS ALKYLATED IN POSITION 1 AND THEIR ESTERS; THEIR PRODUCTION AND USE | FLEISCHHACKER WILHELM (AT) | 1990-11-01 | — | — | WO | claimed |