Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10475650 | 0.88 | MTNR1A (0.44) | P2RX7CAPN1ITGB1ITGA4MTNR1A | |
| SCHEMBL10474756 | 0.87 | CYP2C9 (0.44) | P2RX7CAPN1ITGB1ITGA4MTNR1A | |
| SCHEMBL31706028 | 0.82 | ITGB1 (0.47) | P2RX7CAPN1ITGB1ITGA4MTNR1A | |
| SCHEMBL30829326 | 0.82 | HCRTR1 (0.47) | P2RX7CAPN1MTNR1AMTNR1BTP53 | |
| SCHEMBL7275104 | 0.82 | HCRTR1 (0.47) | P2RX7CAPN1MTNR1AMTNR1BTP53 | |
| SCHEMBL7275111 | 0.82 | HCRTR1 (0.47) | P2RX7CAPN1MTNR1AMTNR1BTP53 | |
| SCHEMBL6703838 | 0.80 | TP53 (0.46) | P2RX7CAPN1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL10475651 | 0.80 | PTGER4 (0.46) | P2RX7MTNR1AMTNR1B | |
| SCHEMBL20193827 | 0.79 | HCRTR1 (0.46) | P2RX7CAPN1MTNR1ATP53MDM2 | |
| SCHEMBL7276858 | 0.79 | HCRTR1 (0.48) | P2RX7CAPN1MTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990012787-A1 | ENANTIOMER-PURE 5-OXO-2-PYRROLIDINE-PROPANE ACIDS ALKYLATED IN POSITION 1 AND THEIR ESTERS; THEIR PRODUCTION AND USE | FLEISCHHACKER WILHELM (AT) | 1990-11-01 | — | — | WO | disclosed |