Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4B | O94953 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921065 | 0.85 | DRD2 (0.63) | DRD2DRD4GRM2CHRM4HTR2C | |
| SCHEMBL9311321 | 0.82 | DRD2 (0.66) | DRD2DRD4GRM2CHRM4HTR2C | |
| SCHEMBL4823773 | 0.79 | DRD2 (1.00) | DRD2DRD4GRM2HTR2CSIGMAR1 | |
| SCHEMBL9422688 | 0.78 | DRD2 (0.63) | DRD2DRD4GRM2HRH3CHRM4 | |
| Hydrochloric Acid SCHEMBL9305904 | 0.77 | DRD2 (0.62) | DRD2DRD4GRM2HRH3CHRM4 | |
| SCHEMBL27782533 | 0.77 | DRD2 (0.58) | DRD2DRD4GRM2CHRM4HTR2C | |
| SCHEMBL4824740 | 0.77 | DRD2 (0.85) | DRD2DRD4GRM2HTR2C | |
| SCHEMBL9311044 | 0.75 | DRD2 (0.66) | DRD2DRD4GRM2HRH3SIGMAR1 | |
| SCHEMBL9667283 | 0.75 | CHRM4 (0.69) | DRD2DRD4GRM2CHRM4HTR2C | |
| SCHEMBL11822283 | 0.75 | DRD2 (0.69) | DRD2DRD4GRM2CHRM4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990006303-A1 | ARYLPIPERIDINE DERIVATIVES | PFIZER INC. (US) | 1990-06-14 | — | — | WO | disclosed |