Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048335 | 0.90 | TAS2R14 (0.48) | MAPTTAAR1KMT2AMEN1TSHR | |
| SCHEMBL189440 | 0.80 | MAPT (0.60) | MAPTTAAR1KMT2AMEN1ACHE | |
| SCHEMBL329228 | 0.78 | SLC6A4 (0.48) | MAPTTAAR1KMT2AMEN1TSHR | |
| Bromide SCHEMBL20912804 | 0.78 | MAPT (0.58) | MAPTTAAR1KMT2AMEN1ACHE | |
| Water SCHEMBL20912805 | 0.78 | MAPT (0.58) | MAPTTAAR1KMT2AMEN1ACHE | |
| SCHEMBL16004807 | 0.76 | MAPT (0.52) | MAPTTAAR1KMT2AMEN1ACHE | |
| SCHEMBL27301457 | 0.76 | SLC6A4 (0.47) | MAPTTAAR1KMT2AMEN1TSHR | |
| SCHEMBL8576431 | 0.76 | GABRA1 (0.46) | MAPTALDH1A1 | |
| SCHEMBL17710493 | 0.76 | MAPT (0.43) | MAPTTAAR1KMT2AMEN1ACHE | |
| SCHEMBL12677859 | 0.74 | MAPT (0.70) | MAPTTAAR1KMT2AMEN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797504-A | HYDROXYLAMINES AND PHENYLENEDIAMINE DERIVATIVES | BETZ LABORATORIES, INC. (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0266906-A2 | Method and composition for inhibiting acrylate ester polymerization | BETZ EUROPE, INC. (US) | 1988-05-11 | — | — | EP | disclosed |
| US-4703073-A | DISCOLORATION INHIBITION | CIBA-GEIGY CORPORATION (US) | 1987-10-27 | — | — | US | disclosed |