Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477348 | 1.00 | ITGB3 (0.39) | ITGB3ITGA2BACEACE2SMN1; SMN2 | |
| SCHEMBL10477366 | 0.93 | ITGB1 (0.41) | ITGB3ITGA2BACEACE2SMN1; SMN2 | |
| SCHEMBL6015436 | 0.88 | ITGB1 (0.43) | ITGB3ITGA2BSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL10477488 | 0.88 | ITGB1 (0.43) | ITGB3ITGA2BSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL2252894 | 0.80 | FOLH1 (0.56) | ITGB3ITGA2BACEACE2SMN1; SMN2 | |
| SCHEMBL10477354 | 0.80 | ACE (0.51) | ITGB3ITGA2BACECTSK | |
| SCHEMBL11370729 | 0.80 | ACE (0.51) | ITGB3ITGA2BACECTSK | |
| SCHEMBL2252892 | 0.80 | FOLH1 (0.56) | ITGB3ITGA2BACEACE2SMN1; SMN2 | |
| SCHEMBL2149054 | 0.79 | POLB (0.45) | ITGB3ITGA2BITGB1ITGA4ALDH1A1 | |
| SCHEMBL1721256 | 0.79 | ITGB3 (0.41) | ITGB3ITGA2BACEACE2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4879398-A | Process for producing 2,6-disubstituted tyrosine | MONSANTO COMPANY (US) | 1989-11-07 | — | — | US | disclosed |