Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015436 | 1.00 | ITGB1 (0.43) | ITGB1ITGA4ESR1SMN1; SMN2NPC1 | |
| SCHEMBL10477366 | 0.93 | ITGB1 (0.41) | ITGB1ITGA4ESR1SMN1; SMN2NPC1 | |
| SCHEMBL10477348 | 0.88 | ITGB3 (0.39) | ITGB1ITGA4SMN1; SMN2NPC1HPGD | |
| SCHEMBL10477347 | 0.88 | ITGB3 (0.39) | ITGB1ITGA4SMN1; SMN2NPC1HPGD | |
| SCHEMBL5279759 | 0.87 | NPC1 (0.46) | ITGB1ITGA4ESR1SMN1; SMN2NPC1 | |
| SCHEMBL10477428 | 0.86 | ITGB1 (0.44) | ITGB1ITGA4SMN1; SMN2NPC1HPGD | |
| SCHEMBL10477426 | 0.86 | ITGB1 (0.44) | ITGB1ITGA4SMN1; SMN2NPC1HPGD | |
| SCHEMBL25469278 | 0.81 | CTSK (0.44) | ESR1HPGDCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL18072612 | 0.80 | CTSK (0.52) | NPC1RAB9AITGB3ITGA2B | |
| SCHEMBL17073710 | 0.80 | CTSK (0.52) | NPC1RAB9AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4879398-A | Process for producing 2,6-disubstituted tyrosine | MONSANTO COMPANY (US) | 1989-11-07 | — | — | US | disclosed |