Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721256 | 0.84 | ITGB3 (0.41) | TSHRITGB3ITGA2BITGB1ITGA4 | |
| SCHEMBL8485515 | 0.82 | FPR2 (0.54) | ITGB3ITGA2BITGB1ITGA4CA2 | |
| SCHEMBL2320402 | 0.82 | FPR2 (0.54) | ITGB3ITGA2BITGB1ITGA4CA2 | |
| SCHEMBL5502788 | 0.82 | FPR2 (0.52) | POLBITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL1310039 | 0.81 | PTPN1 (0.53) | POLBITGB3ITGA2BITGA4 | |
| SCHEMBL6251044 | 0.81 | ITGB3 (0.41) | TSHRITGB3ITGA2BITGB1ITGA4 | |
| SCHEMBL5199846 | 0.80 | ALDH1A1 (0.41) | TSHRITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL5088784 | 0.79 | ALDH1A1 (0.52) | TSHRITGB3ITGA2BITGA4ALDH1A1 | |
| SCHEMBL10477347 | 0.79 | ITGB3 (0.39) | TSHRITGB3ITGA2BITGB1ITGA4 | |
| SCHEMBL10477348 | 0.79 | ITGB3 (0.39) | TSHRITGB3ITGA2BITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |