Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198122 | 0.86 | LMNA (0.51) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL9193057 | 0.80 | TDP1 (0.44) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL31633573 | 0.79 | CA12 (0.57) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL537892 | 0.78 | TDP1 (0.64) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL7604891 | 0.78 | TSHR (0.56) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL10451338 | 0.77 | TDP1 (0.50) | TDP1MAPTMEN1KMT2APOLB | |
| Fluoride SCHEMBL27394412 | 0.77 | TDP1 (0.62) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL17065000 | 0.76 | CA12 (0.51) | TDP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL720358 | 0.76 | TDP1 (0.79) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL22547092 | 0.74 | CA12 (0.65) | TDP1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328203-A2 | [5(6) (1H-azole-1-ylmethyl)benzimidazole] carbamates | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-08-16 | — | — | EP | disclosed |
| US-4826862-A | Anthelminthic [(5(6) (1H-azole-1-ylmethyl)benzimidazole]carbamates | JANSSEN PHARMACEUTICA, N.V. (BE) | 1989-05-02 | — | — | US | disclosed |