SCHEMBL537892

SCHEMBL537892

Nc1ccc(F)cc1[N+](=O)[O-]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.64
ALDH1A1 P00352 4/20 0.64
MEN1 O00255 2/20 0.64
POLB P06746 2/20 0.64
KMT2A Q03164 2/20 0.64
MAPT P10636 2/20 0.64
CYP3A4 P08684 1/20 0.64
ALOX15 P16050 1/20 0.64
TSHR P16473 2/20 0.60
ATM Q13315 1/20 0.59
LMNA P02545 1/20 0.55
PDE7A Q13946 1/20 0.54
PKM P14618 1/20 0.50
HIF1A Q16665 1/20 0.47
HSPB1 P04792 2/20 0.46
NPSR1 Q6W5P4 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
GPR35 Q9HC97 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27394412 0.98 TDP1 (0.62) TDP1ALDH1A1MEN1POLBKMT2A
SCHEMBL720358 0.85 TDP1 (0.79) TDP1ALDH1A1MEN1POLBKMT2A
SCHEMBL77039 0.83 TDP1 (0.64) TDP1ALDH1A1MEN1POLBKMT2A
SCHEMBL29655271 0.82 TDP1 (0.62) TDP1ALDH1A1MEN1POLBKMT2A
SCHEMBL29655008 0.81 TDP1 (0.71) TDP1ALDH1A1MEN1POLBKMT2A
SCHEMBL27677622 0.81 VCAM1 (0.60) TDP1ALDH1A1MEN1POLBKMT2A
SCHEMBL721310 0.81 TDP1 (0.71) TDP1ALDH1A1MEN1POLBKMT2A
SCHEMBL29745239 0.80 TDP1 (0.72) TDP1ALDH1A1CYP3A4TSHRATM
SCHEMBL216553 0.80 TDP1 (0.72) TDP1ALDH1A1CYP3A4TSHRATM
SCHEMBL10477444 0.79 LMNA (0.64) TDP1ALDH1A1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 747 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119931105-A Polyimide composite flexible film based on magnetron sputtering and preparation method thereof 圭胜(南通)新材料科技有限公司 2025-05-06 CN claimed
CN-111018717-A Method for synthesizing 4-fluoro-2-nitroaniline by using microchannel reactor 成都艾必克医药科技有限公司 2020-04-17 CN claimed
US-20180355099-A1 Fluorinated Benzoxadiazole-Based Donor-Acceptor Polymers for Electronic and Photonic Applications THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2018-12-13 US claimed
EP-1506196-B1 PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS ICAGEN INC (US) 2012-01-18 EP claimed
CN-1243007-C Bismuth color reagent of azofluorophosphine-DBF and its synthesis and use UNIV EAST CHINA NORMAL (CN) 2006-02-22 CN claimed
CN-1206233-C Synthesis and use of novel thorium color developing reagent metafluoro azo fluorophosphine UNIV EAST CHINA NORMAL (CN) 2005-06-15 CN claimed
CN-1456565-A Bismuth color reagent of azofluorophosphine-DBF and its synthesis and use UNIV HUADONG (CN) 2003-11-19 CN claimed
CN-1450071-A Synthesis and use of novel thorium color developing reagent metafluoro azo fluorophosphine UNIV EAST CHINA NORMAL (CN) 2003-10-22 CN claimed
CN-122094953-A 1, 3-Dihydro-2H-pyrrolo [3,4-c ] quinoline derivatives as cGAS inhibitors for the treatment of inflammatory and/or autoimmune diseases 2026-05-26 CN disclosed
US-20260138966-A1 WNT SIGNALING PATHWAY INHIBITORS FOR TREATMENTS OF DISEASE UNIV OF MARYLAND BALTIMORE (US) 2026-05-21 US disclosed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
US-20260124214-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER ARTIOS PHARMA LIMITED (GB) 2026-05-07 US disclosed
US-20260034142-A1 Therapeutic Compounds and Compositions for Treating Social Disorders and Substance Use Disorders Kinoxis Therapeutics Pty Ltd (AU) 2026-02-05 US disclosed
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-11-27 US disclosed
US-4263441-A BENZOXAZOLE DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1981-04-21 US disclosed
US-4167638-A Process for production of 8-NHR quinolines THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1979-09-11 US disclosed
EP-0002030-A1 Fluorinated benzazole derivatives, method for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-30 EP disclosed
US-4138571-A Nitrophenyl imino propionates GAF CORPORATION (US) 1979-02-06 US disclosed
US-4113954-A PROCESS FOR THE PREPARATION OF 3-ANILINO-5-PYRAZOLONES GAF CORPORATION (US) 1978-09-12 US disclosed
US-3957860-A SULFAMIC ACID CIBA-GEIGY AG (CH) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124214-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER CBR1, NR3C1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 TDP1 1135/4885ALDH1A1 1397/4885MEN1 2710/4885
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS DGKG, DGKB, DGKK TDP1 2436/4885ALDH1A1 4095/4885MEN1 4106/4885
US-20180355099-A1 Fluorinated Benzoxadiazole-Based Donor-Acceptor Polymers for Electronic and Photonic Applications FTO, PPOX, FOXO3 TDP1 956/4885ALDH1A1 1862/4885MEN1 3406/4885
US-20260138966-A1 WNT SIGNALING PATHWAY INHIBITORS FOR TREATMENTS OF DISEASE CTNNB1, WNT1, CTNND1 TDP1 4819/4885ALDH1A1 3230/4885MEN1 4746/4885
US-20260034142-A1 Therapeutic Compounds and Compositions for Treating Social Disorders and Substance Use Disorders SLC6A3, SLC6A4, SLC6A1 TDP1 1120/4885ALDH1A1 210/4885MEN1 4434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.