Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477988 | 0.85 | PKM (0.43) | PKMHTTPOLBHSD17B1TYR | |
| SCHEMBL11290412 | 0.83 | PKM (0.64) | PKMHTTPOLBHSD17B1KMT2A | |
| SCHEMBL27585879 | 0.81 | MEN1 (0.50) | HTTPOLBTYRKMT2AMEN1 | |
| SCHEMBL9616832 | 0.80 | PKM (0.68) | PKMHTTPOLBHSD17B1KMT2A | |
| SCHEMBL4819345 | 0.79 | SIRT2 (0.41) | PKMHTTPOLBKMT2AMEN1 | |
| SCHEMBL385574 | 0.77 | PKM (0.75) | PKMHTTPOLBHSD17B1KMT2A | |
| SCHEMBL9644638 | 0.77 | PKM (0.64) | PKMHTTPOLBHSD17B1TYR | |
| SCHEMBL29122249 | 0.76 | TYR (0.59) | PKMTYRALDH1A1 | |
| SCHEMBL11125937 | 0.76 | PKM (0.68) | PKMHTTPOLBHSD17B1KMT2A | |
| SCHEMBL8845203 | 0.75 | PKM (0.72) | PKMHTTPOLBHSD17B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853381-A | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0162576-B1 | ETHANOLAMINE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1989-07-26 | — | — | EP | disclosed |
| EP-0162576-A1 | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1985-11-27 | — | — | EP | disclosed |