Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27949329 | 0.84 | HPGD (0.50) | SIRT2ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL27728433 | 0.81 | CHRM2 (0.44) | SIRT2ALDH1A1MAOAMAPTMEN1 | |
| SCHEMBL4810977 | 0.80 | PKM (0.47) | ALDH1A1MAPK1ADRB2MRGPRX4MAOA | |
| SCHEMBL27974256 | 0.80 | POLB (0.43) | ALDH1A1MAOAMAPTMEN1KMT2A | |
| SCHEMBL10477756 | 0.79 | PKM (0.60) | ALDH1A1PKMMEN1KMT2AHTT | |
| SCHEMBL16728864 | 0.78 | TAS1R3 (0.49) | ALDH1A1MAPK1ADRB2MRGPRX4MAOA | |
| SCHEMBL10499879 | 0.77 | MAOA (0.46) | SIRT2ALDH1A1MAOAMAOBMAPT | |
| SCHEMBL30665778 | 0.76 | CYP2D6 (0.42) | ALDH1A1MAPK1ADRB2MRGPRX4MAOA | |
| SCHEMBL17831661 | 0.76 | CYP2D6 (0.42) | ALDH1A1MAPK1ADRB2MRGPRX4MAOA | |
| SCHEMBL15492066 | 0.75 | PKM (0.44) | ALDH1A1MAPK1ADRB2MRGPRX4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468364-B2 | Carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| US-7468364-B2 | Carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| US-7468364-B2 | Carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| US-20060183730-A1 | Novel carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2006-08-17 | — | — | US | disclosed |
| EP-1612211-A1 | NOVEL CARBAPENEM COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183730-A1 | Novel carbapenem compounds | MGAM, SI, MCRS1 | SIRT2 1457/4885ALDH1A1 1294/4885MAPK1 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.