Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.62 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616832 | 0.86 | PKM (0.68) | PKMHSD17B1POLBHTTHSP90AA1 | |
| SCHEMBL8845203 | 0.86 | PKM (0.72) | PKMHSD17B1POLBHTTHSP90AA1 | |
| SCHEMBL9574305 | 0.86 | PKM (1.00) | PKMHSD17B1POLBHTTHSP90AA1 | |
| SCHEMBL9763047 | 0.85 | HSP90AA1 (0.65) | PKMHSD17B1POLBHTTHSP90AA1 | |
| SCHEMBL4096708 | 0.85 | HSD17B1 (1.00) | PKMHSD17B1POLBHTTHSP90AA1 | |
| SCHEMBL29291399 | 0.84 | PKM (0.70) | PKMHSD17B1POLBHTTHSP90AA1 | |
| SCHEMBL469648 | 0.84 | PKM (0.70) | PKMHSD17B1POLBHTTHSP90AA1 | |
| SCHEMBL10743832 | 0.84 | PKM (0.70) | PKMHSD17B1POLBHTTHSP90AA1 | |
| SCHEMBL9644638 | 0.83 | PKM (0.64) | PKMHSD17B1POLBHTTHSP90AA1 | |
| SCHEMBL335280 | 0.83 | POLB (0.97) | PKMHSD17B1POLBHTTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974586-A | Colorful heat-preservation soft porcelain and preparation method thereof | 颜如玉 | 2023-04-18 | — | — | CN | claimed |
| CN-115974586-A | Colorful heat-preservation soft porcelain and preparation method thereof | 颜如玉 | 2023-04-18 | — | — | CN | disclosed |
| CN-115974586-A | Colorful heat-preservation soft porcelain and preparation method thereof | 颜如玉 | 2023-04-18 | — | — | CN | disclosed |
| EP-2330098-B1 | COMPOUND WITH AGITATION EFFECT ON PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR SUBTYPE delta, AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2015-04-29 | — | — | EP | disclosed |
| US-8822519-B2 | Compound with agitation effect on peroxisome proliferator-activated receptor process for its preparation and use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2014-09-02 | — | — | US | disclosed |
| CN-102112452-B | Compound with agonism on delta subtype peroxidase proliferator activated receptor, preparation method and application thereof | ZHEJIANG HISUN PHARMACEUTICAL | 2014-05-14 | — | — | CN | disclosed |
| CN-101643451-B | Peroxisome proliferator-activated receptor subtype delta agonist compound and preparation method thereof | ZHEJIANG HISUN PHARM CO LTD | 2013-03-06 | — | — | CN | disclosed |
| US-8101625-B2 | Pyrimidinones as Casein Kinase II (CK2) modulators | EXELIXIS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110319458-A1 | COMPOUND WITH AGITATION EFFECT ON PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR. PROCESS FOR ITS PREPARATION AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2011-12-29 | — | — | US | disclosed |
| EP-1948617-B1 | PYRIMIDINONES AS CASEIN KINASE II (CK2) MODULATORS | EXELIXIS INC (US) | 2011-07-27 | — | — | EP | disclosed |
| US-20090215803-A1 | Pyrimidinones as Casein Kinase II (CK2) Modulators | EXELIXIS, INC. | 2009-08-27 | — | — | US | disclosed |
| US-6949536-B2 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | PFIZER, INC. (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040157824-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | PFIZER INC. | 2004-08-12 | — | — | US | disclosed |
| EP-1086097-B1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER (US) | 2004-05-19 | — | — | EP | disclosed |
| US-6727238-B2 | CYCLOOXYGENASE INHIBITORS | PFIZER INC. | 2004-04-27 | — | — | US | disclosed |
| US-20030225064-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | ANDO KAZUO (JP) | 2003-12-04 | — | — | US | disclosed |
| US-6608095-B2 | Sulfonylbenzene and sulfonamidobenzene compounds which inhibit COX-2; treatment of a medical condition in which prostaglandins are implicated as pathogens | PFIZER INC. | 2003-08-19 | — | — | US | disclosed |
| US-20020045654-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | ANDO KAZUO (JP) | 2002-04-18 | — | — | US | disclosed |
| US-6294558-B1 | ANTIINFLAMMATORY AGENTS AND PROSTAGLANTINS | PFIZER INC. | 2001-09-25 | — | — | US | disclosed |
| US-5113019-A | PROCESS FOR PHENOL ALKYLTHIOLATION AND ITS APPLICATION TO THE SYNTHESIS OF 4-ACYL-2-ALKYLTHIOPHENOLS | SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) | 1992-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157824-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | CNR1, PTGS1, PTGER1 | PKM 3087/4885HSD17B1 515/4885POLB 4325/4885 |
| US-20020045654-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | CNR1, PTGER1, PTGS1 | PKM 3481/4885HSD17B1 532/4885POLB 4345/4885 |
| US-20110319458-A1 | COMPOUND WITH AGITATION EFFECT ON PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR. PROCESS FOR ITS PREPARATION AND USE THEREOF | PPARG, PPARD, PPARA | PKM 277/4885HSD17B1 294/4885POLB 711/4885 |
| US-20030225064-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | CNR1, PTGS1, PTGER1 | PKM 3087/4885HSD17B1 515/4885POLB 4325/4885 |
| US-20090215803-A1 | Pyrimidinones as Casein Kinase II (CK2) Modulators | CSNK2A1, CSNK1A1, CSNK2A2 | PKM 260/4885HSD17B1 3103/4885POLB 1373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.