Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478397 | 0.83 | OPRM1 (0.51) | DRD4OPRM1CHRNA7CYP2D6KCNH2 | |
| SCHEMBL10099948 | 0.83 | S1PR1 (0.56) | HTTNOTUMS1PR1S1PR3NR1H4 | |
| Hydrochloric Acid SCHEMBL10478268 | 0.82 | OPRM1 (0.50) | DRD4OPRM1CHRNA7CYP2D6KCNH2 | |
| SCHEMBL10620938 | 0.81 | OPRM1 (0.53) | OPRM1HTTMAPTNOTUMS1PR1 | |
| Hydrochloric Acid SCHEMBL10478033 | 0.80 | OPRM1 (0.51) | OPRM1HTTNOTUMS1PR1S1PR3 | |
| Oxalic Acid SCHEMBL10478220 | 0.78 | MAPT (0.44) | HTTMAPTNPC1RAB9A | |
| Oxalic Acid SCHEMBL10478270 | 0.78 | MAPT (0.39) | DRD4OPRM1MAPTS1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL10478080 | 0.78 | OPRM1 (0.46) | DRD4OPRM1NR1H4CYP2D6KCNH2 | |
| Oxalic Acid SCHEMBL10478394 | 0.78 | KMT2A (0.43) | OPRM1HCRTR1HCRTR2 | |
| Oxalic Acid SCHEMBL10478168 | 0.77 | LMNA (0.42) | DRD4OPRM1MAPTHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845095-A | ANALGESICS, NEUROLEPTICS | A/S FERROSAN (DK) | 1989-07-04 | — | — | US | claimed |
| EP-0285032-A1 | 4-Phenylpiperidine compounds and their preparation and use | A/S FERROSAN (DK) | 1988-10-05 | — | — | EP | claimed |
| US-4845095-A | ANALGESICS, NEUROLEPTICS | A/S FERROSAN (DK) | 1989-07-04 | — | — | US | disclosed |