SCHEMBL10478673

SCHEMBL10478673

CN(CC(N)=O)S(=O)(=O)Cc1cccc(Br)c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EGFR P00533 5/20 0.42
ERBB2 P04626 5/20 0.42
RIPK1 Q13546 1/20 0.42
TAAR1 Q96RJ0 2/20 0.42
KMT2A Q03164 2/20 0.40
PARP15 Q460N3 1/20 0.40
PARP14 Q460N5 1/20 0.40
PARP10 Q53GL7 1/20 0.40
MAPK8 P45983 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP14 P50281 1/20 0.39
ADAM17 P78536 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PARP1 P09874 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10478577 0.88 TAAR1 (0.41) EGFRERBB2RIPK1TAAR1KMT2A
SCHEMBL10478480 0.87 EGFR (0.46) EGFRERBB2RIPK1TAAR1KMT2A
SCHEMBL10478763 0.84 CYP3A4 (0.41)
SCHEMBL10478812 0.84 RORC (0.41) EGFRERBB2RIPK1KMT2APARP15
SCHEMBL10478827 0.83 LMNA (0.46) KMT2AMAPK8LMNASMN1; SMN2
SCHEMBL10478457 0.83 KMT2A (0.43) RIPK1TAAR1KMT2APARP10MAPK8
SCHEMBL10478544 0.81 ACHE (0.40) LMNA
SCHEMBL10478808 0.81 LMNA (0.46) TAAR1MAPK8LMNASMN1; SMN2PARP1
SCHEMBL10478694 0.80 EPHX1 (0.47) TAAR1KMT2AMAPK8LMNA
SCHEMBL10478828 0.80 XIAP (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4885027-A PLANT GROWTH REGULATORS; NONPHYTOTOXIC; PRE- AND POST EMERGENCE CHEVRON RESEARCH COMPANY (US) 1989-12-05 US disclosed