Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478509 | 0.90 | EGFR (0.34) | EGFRERBB2KMT2AMEN1HTT | |
| SCHEMBL10494542 | 0.81 | RORC (0.34) | EGFRERBB2KMT2AMEN1HTT | |
| SCHEMBL10478812 | 0.79 | RORC (0.41) | EGFRERBB2KMT2AMEN1HTT | |
| SCHEMBL10478499 | 0.79 | CNR2 (0.46) | EGFRERBB2KMT2AMEN1HTT | |
| SCHEMBL10478749 | 0.78 | HTR6 (0.38) | KMT2AMEN1RORCPARP10 | |
| SCHEMBL10478590 | 0.78 | RORC (0.37) | KMT2AMEN1RORC | |
| SCHEMBL10478915 | 0.76 | RORC (0.39) | EGFRERBB2KMT2AMEN1HTT | |
| SCHEMBL10478578 | 0.76 | EGFR (0.38) | EGFRERBB2KMT2AMEN1HTT | |
| SCHEMBL10478772 | 0.75 | S1PR2 (0.41) | KMT2AMEN1 | |
| SCHEMBL10478673 | 0.74 | EGFR (0.42) | EGFRERBB2KMT2APARP15PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885027-A | PLANT GROWTH REGULATORS; NONPHYTOTOXIC; PRE- AND POST EMERGENCE | CHEVRON RESEARCH COMPANY (US) | 1989-12-05 | — | — | US | disclosed |