SCHEMBL1047893

SCHEMBL1047893

Oc1c(CF)cc(CF)cc1CF

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
CASP6 P55212 1/20 0.33
SHBG P04278 1/20 0.32
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27579195 0.75 MAPK1 (0.33) KDM4ECYP2C9ALOX15HSD17B10
SCHEMBL1047527 0.74 KDM4E (0.31) KDM4ECASP6SHBG
SCHEMBL13890777 0.72
SCHEMBL1047330 0.72
SCHEMBL4232261 0.72
SCHEMBL1047892 0.72
SCHEMBL1651131 0.72
SCHEMBL8993656 0.71 ACHE (0.48) HSD17B10
SCHEMBL17906583 0.70 PTPN1 (0.32) KDM4EHSD17B10
SCHEMBL11613629 0.69 GABRA1 (0.55) ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110139844-A The method for being used to prepare the polyethylene wax of polymerization SCG化学有限公司 2019-08-16 CN claimed
CN-109503636-A A kind of synthetic method of 2,4,6- trifluoromethyl phenol 杭州澳赛诺生物科技有限公司 2019-03-22 CN claimed
CN-104876860-B A kind of diaryl pyrazole piperidine derivatives and preparation method and application 山东大学 2018-02-13 CN claimed
CN-107652165-A A kind of purification process of the trifluoromethyl phenol of liquid crystal intermediates 3,4,5 常州润联化工有限公司 2018-02-02 CN claimed
CN-104876860-A Diaryl pyridine derivative as well as preparation method and application thereof UNIV SHANDONG 2015-09-02 CN claimed
CN-104016990-A Imidazopyrazine derivatives as well as preparation method and application thereof UNIV SHANDONG 2014-09-03 CN claimed
CN-103930452-A Process for producing polyolefins using a catalyst system UNIVATION TECH LLC 2014-07-16 CN claimed
CN-102108044-B Purification method of liquid crystal intermediate 3,4,5-trifluoro phenol CHANGZHOU JIEN CHEMICAL CO LTD 2013-09-25 CN claimed
CN-102108044-A Purification method of liquid crystal intermediate 3,4,5-trifluoro phenol CHANGZHOU JIEN CHEMICAL CO LTD 2011-06-29 CN claimed
CN-106061504-B Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and uses thereof 詹森药业有限公司 2019-09-06 CN disclosed
CN-110139844-A The method for being used to prepare the polyethylene wax of polymerization SCG化学有限公司 2019-08-16 CN disclosed
CN-110088077-A (meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社尼康 2019-08-02 CN disclosed
CN-109999033-A Positive allosteric modulator or the combination of normotopia agonist including metabotropic glutamate energy receptor subtype 2 and application thereof 詹森药业有限公司 2019-07-12 CN disclosed
CN-109999025-A Positive allosteric modulator or the combination of normotopia agonist including metabotropic glutamate energy receptor subtype 2 and application thereof 詹森药业有限公司 2019-07-12 CN disclosed
CN-1408738-A Catalytic component for addition polymerization, process for producing addition polymerization and process for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2003-04-09 CN disclosed
CN-1339040-A Catalyst for stereoregular polymerization of 2-olefin and process for producing stereoregular-olefin polymer SUMITOMO CHEMICAL CO (JP) 2002-03-06 CN disclosed
CN-1306011-A Polyaddition catalyst component, polyaddition catalyst and method for preparing addition polymer SUMITOMO CHEMICAL CO (JP) 2001-08-01 CN disclosed
CN-1302820-A Modified particle, olefin polymerization catalyst using the same, and process for producing olefin polymer SUMITOMO CHEMICAL CO (JP) 2001-07-11 CN disclosed
CN-1263882-A Method for preparing fluorine-substituted aromatic compound MITSUI CHEMICALS INC (JP) 2000-08-23 CN disclosed
CN-1242779-A Modified particles, carrier prepared therefrom, olefin polymerization catalyst component prepared therefrom, olefin polymerization catalyst prepared therefrom, and process for preparing olefin polymer SUMITOMO CHEMICAL CO (JP) 2000-01-26 CN disclosed