Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479114 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDMAPTNPC1POLB | |
| SCHEMBL9224065 | 0.78 | RXFP1 (0.49) | ALDH1A1HPGDMAPTNPC1POLB | |
| SCHEMBL10479125 | 0.75 | ALDH1A1 (0.37) | ALDH1A1HPGDMAPTNPC1POLB | |
| SCHEMBL31350567 | 0.74 | DYRK1A (0.51) | ALDH1A1HPGDMAPTNPC1POLB | |
| SCHEMBL13414547 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTNPC1POLB | |
| SCHEMBL11108522 | 0.72 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTNPC1POLB | |
| SCHEMBL4088610 | 0.72 | POLB (0.43) | ALDH1A1HPGDMAPTNPC1POLB | |
| SCHEMBL9631166 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HPGDNPC1POLBRAB9A | |
| SCHEMBL23754035 | 0.70 | ERN1 (0.36) | ALDH1A1MAPTPOLBKMT2AKDM4E | |
| SCHEMBL9631026 | 0.70 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818753-A | FUNGICIDES; SYNERGISTIC EFFECT WITH SULFA DRUGS | SRI INTERNATIONAL (US) | 1989-04-04 | — | — | US | disclosed |