Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479114 | 0.83 | ALDH1A1 (0.46) | RXFP1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10479125 | 0.80 | ALDH1A1 (0.37) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL1601224 | 0.79 | RXFP1 (0.58) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL10479142 | 0.78 | ALDH1A1 (0.38) | RXFP1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2322798 | 0.78 | RXFP1 (0.56) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL13414547 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL31353606 | 0.75 | CXCR1 (0.31) | RXFP1ALDH1A1CXCR1CXCR2MEN1 | |
| SCHEMBL11932852 | 0.75 | RXFP1 (0.53) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL9631166 | 0.73 | ALDH1A1 (0.59) | RXFP1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9631026 | 0.72 | ALDH1A1 (0.43) | CA1CA2CA9ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384423-A | Intermediates for antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1995-01-24 | — | — | US | disclosed |
| US-5240960-A | Antiinflammatory agents | ROUSSEL UCLAF (FR) | 1993-08-31 | — | — | US | disclosed |