Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10767715 | 0.80 | TAS1R3 (0.46) | ALDH1A1CXCR1CXCR2KDM4EPOLB | |
| SCHEMBL13414547 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10POLBMEN1 | |
| SCHEMBL11443101 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA9KDM4E | |
| SCHEMBL10479114 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBLMNAMEN1 | |
| SCHEMBL13170059 | 0.73 | ALDH1A1 (0.54) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL9658598 | 0.73 | PDK1 (0.62) | ALDH1A1CA1CA2CA9CXCR1 | |
| SCHEMBL9224065 | 0.72 | RXFP1 (0.49) | ALDH1A1CA1CA2CA9CXCR1 | |
| SCHEMBL13199450 | 0.72 | AR (0.47) | ALDH1A1CXCR1CXCR2KDM4EHPGD | |
| SCHEMBL8558945 | 0.72 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA9KDM4E | |
| SCHEMBL8928864 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10POLBPARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206281-B1 | PROCESS FOR CONVERTING CRUDE ISOINDOLINE PIGMENTS INTO A PIGMENTARY FORM | BASF Aktiengesellschaft (DE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0206281-A2 | Process for converting crude isoindoline pigments into a pigmentary form | BASF Aktiengesellschaft (DE) | 1986-12-30 | — | — | EP | disclosed |