Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273210 | 0.83 | CYP1A2 (0.40) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL7026891 | 0.82 | ACHE (0.38) | MAPTKDM4ETDP1TSHRRAB9A | |
| Perchlorate SCHEMBL31344129 | 0.81 | ACHE (0.36) | RAB9AMEN1KMT2APOLBACHE | |
| SCHEMBL9696995 | 0.78 | ALDH1A1 (0.40) | MAPTKDM4ETDP1TSHRRAB9A | |
| SCHEMBL2773903 | 0.71 | CYP2A6 (0.48) | MAPTALDH1A1ACHEHTT | |
| SCHEMBL19329417 | 0.71 | ATM (0.50) | MAPTKDM4ETDP1TSHRRAB9A | |
| SCHEMBL2315874 | 0.71 | ATM (0.50) | MAPTKDM4ETDP1TSHRRAB9A | |
| Iodide SCHEMBL3905319 | 0.70 | CYP2A6 (0.47) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5248911 | 0.67 | TSHR (0.66) | MAPTTDP1TSHRRAB9AMEN1 | |
| SCHEMBL29562542 | 0.65 | ACHE (0.59) | MAPTKDM4ERAB9AACHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989006231-A1 | ASSAYS UTILIZING IMPROVED CHEMILUMINESCENT ESTERS, THIOESTERS AND AMIDES | LONDON DIAGNOSTICS, INC. (US) | 1989-07-13 | — | — | WO | disclosed |