Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.58 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.58 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 11/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480960 | 1.00 | PIM1 (0.58) | PIM1PIM2PIM3HPGDPTPN1 | |
| SCHEMBL9371966 | 0.95 | PIM1 (0.65) | PIM1PIM2PIM3HPGDPTPN1 | |
| SCHEMBL9371962 | 0.95 | PIM1 (0.65) | PIM1PIM2PIM3HPGDPTPN1 | |
| SCHEMBL9372921 | 0.83 | HPGD (0.67) | PIM1PIM2PIM3HPGDPTPN1 | |
| SCHEMBL9372915 | 0.83 | HPGD (0.67) | PIM1PIM2PIM3HPGDPTPN1 | |
| Benzaldehyde SCHEMBL10480890 | 0.82 | PIM1 (0.86) | PIM1PIM2PIM3HPGDMAOA | |
| Benzaldehyde SCHEMBL10480742 | 0.82 | PIM1 (0.86) | PIM1PIM2PIM3HPGDMAOA | |
| SCHEMBL510481 | 0.81 | MAOA (0.53) | MAOAMAOBPOLBMEN1KMT2A | |
| SCHEMBL9375247 | 0.80 | HPGD (0.68) | PIM1PIM2PIM3HPGDPTPN1 | |
| SCHEMBL9375243 | 0.80 | HPGD (0.68) | PIM1PIM2PIM3HPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989008650-A1 | THIAZOLIDINEDIONE HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1989-09-21 | — | — | WO | disclosed |