Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28309482 | 0.82 | — | — | |
| SCHEMBL9241724 | 0.80 | LMNA (0.33) | LMNA | |
| SCHEMBL28291217 | 0.79 | — | — | |
| SCHEMBL10712393 | 0.76 | LMNA (0.31) | LMNA | |
| SCHEMBL6559293 | 0.76 | LMNA (0.31) | LMNA | |
| SCHEMBL23928735 | 0.76 | THRB (0.31) | LMNA | |
| SCHEMBL3175644 | 0.76 | THRB (0.31) | LMNA | |
| SCHEMBL19699318 | 0.76 | THRB (0.31) | LMNA | |
| SCHEMBL7641162 | 0.76 | LMNA (0.42) | LMNA | |
| SCHEMBL7643011 | 0.76 | LMNA (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4798840-A | Coronary-active fluorine-containing 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-17 | — | — | US | claimed |
| US-4798840-A | Coronary-active fluorine-containing 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-17 | — | — | US | disclosed |