SCHEMBL23928735

SCHEMBL23928735

O[CH]CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10431059 0.86
SCHEMBL9241724 0.80 LMNA (0.33) LMNA
SCHEMBL10712393 0.76 LMNA (0.31) LMNA
SCHEMBL6559293 0.76 LMNA (0.31) LMNA
SCHEMBL3175644 0.76 THRB (0.31) THRBLMNA
SCHEMBL19699318 0.76 THRB (0.31) THRBLMNA
SCHEMBL10480973 0.76 LMNA (0.31) LMNA
SCHEMBL7641162 0.76 LMNA (0.42) THRBLMNA
SCHEMBL7643011 0.76 LMNA (0.42) THRBLMNA
SCHEMBL20528038 0.75 LMNA (0.33) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183746-A1 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2023-06-15 US disclosed
CN-115997016-A Composition comprising nucleic acid nanoparticles having modular functional groups 西克斯福德生物科学有限公司 2023-04-21 CN disclosed
EP-4143316-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2023-03-08 EP disclosed
EP-4022058-A2 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2022-07-06 EP disclosed
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2022-06-14 US disclosed
WO-2021220053-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-11-04 WO disclosed
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN THRB 3043/4885LMNA 514/4885
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY NCL, NSUN3, POLN THRB 3043/4885LMNA 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.