Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.61 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660830 | 0.81 | RAB9A (0.58) | KMT2AMEN1MAPTRAB9ARXFP1 | |
| SCHEMBL10481490 | 0.81 | MAPK14 (0.56) | KMT2AMEN1L3MBTL1RAB9ALMNA | |
| SCHEMBL10069116 | 0.76 | TASP1 (1.00) | TASP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL4683413 | 0.73 | KCNK3 (0.88) | P2RX1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL27652617 | 0.73 | RXFP1 (0.88) | P2RX1MAPTPTGS1RXFP1 | |
| SCHEMBL11955716 | 0.73 | F10 (0.55) | KMT2AMEN1MAPTRAB9ARXFP1 | |
| SCHEMBL24141032 | 0.72 | MAPT (0.84) | P2RX1KMT2AMEN1MAPTHTT | |
| Salfluverine SCHEMBL2700016 | 0.72 | P2RX1 (1.00) | P2RX1MAPTPTGS1RXFP1 | |
| SCHEMBL9524357 | 0.72 | KMT2A (0.56) | P2RX1KMT2AMEN1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL29693050 | 0.72 | KCNK3 (0.86) | P2RX1KMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4800211-A | ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1989-01-24 | — | — | US | disclosed |