SCHEMBL1048346

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12994806	0.91	ALDH1A1 (0.48)	ALDH1A1CYP1A1CYP1B1FFAR4CYP3A4
	SCHEMBL31292023	0.89	ALDH1A1 (0.46)	ALDH1A1CYP1A1CYP1B1FFAR4CYP3A4
	SCHEMBL16960556	0.89	ALDH1A1 (0.46)	ALDH1A1CYP1A1CYP1B1FFAR4CYP3A4
	SCHEMBL15718616	0.89	ALDH1A1 (0.46)	ALDH1A1CYP1A1CYP1B1FFAR4CYP3A4
	SCHEMBL17071826	0.89	ALDH1A1 (0.46)	ALDH1A1CYP1A1CYP1B1FFAR4NPC1
	SCHEMBL24436837	0.89	ALDH1A1 (0.46)	ALDH1A1CYP1A1CYP1B1CYP3A4NPC1
	SCHEMBL18781270	0.87	ALDH1A1 (0.44)	ALDH1A1FFAR4GRIN2B
	SCHEMBL15713182	0.85	ALDH1A1 (0.42)	ALDH1A1CYP1A1CYP1B1FFAR4NPC1
	SCHEMBL18770641	0.84	ENPP2 (0.47)	ALDH1A1FFAR4CYP3A4NPC1RAB9A
	SCHEMBL16950420	0.84	GRIN2B (0.42)	ALDH1A1FFAR4CYP4F2CYP4A11PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.