Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | G6PD | P11413 | 2/20 | 0.73 |
| ▸ | PKM | P14618 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | MPI | P34949 | 1/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.69 |
| ▸ | STS | P08842 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883111 | 1.00 | ESR1 (0.73) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL1048371 | 0.89 | ESR1 (0.77) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL31544736 | 0.89 | ESR1 (0.77) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL2596534 | 0.89 | ESR1 (0.77) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL13123060 | 0.89 | ESR1 (0.77) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL224399 | 0.85 | ESR1 (1.00) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL6009933 | 0.85 | ESR1 (1.00) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL13123059 | 0.85 | ESR1 (1.00) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL224398 | 0.85 | ESR1 (1.00) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL29506781 | 0.85 | ESR1 (1.00) | ESR1ESR2LMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012664-A2 | ADMINISTRATION OF ESTRADIOL METABOLITES FOR INHIBITION OF DRUG-INDUCED NEPHROTOXICITY | UNIVERSITY OF PITTSBURGH (US) | 2004-02-12 | — | — | WO | disclosed |