Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484336 | 1.00 | ESR1 (0.53) | ESR1CYP19A1HTR1BHTR1DESRRG | |
| Hydrochloric Acid SCHEMBL10484200 | 0.87 | ESR1 (0.67) | ESR1CYP19A1HTR1BHTR1DESRRG | |
| Hydrochloric Acid SCHEMBL10484192 | 0.87 | ESR1 (0.67) | ESR1CYP19A1HTR1BHTR1DESRRG | |
| SCHEMBL10484164 | 0.85 | ESRRG (0.41) | ESR1CYP19A1ESRRGMEN1KMT2A | |
| SCHEMBL10484157 | 0.85 | ESRRG (0.41) | ESR1CYP19A1ESRRGMEN1KMT2A | |
| SCHEMBL10484100 | 0.85 | ESR1 (0.56) | ESR1ESRRGMEN1KMT2AKDM4E | |
| SCHEMBL10484096 | 0.85 | ESR1 (0.56) | ESR1ESRRGMEN1KMT2AKDM4E | |
| SCHEMBL10484445 | 0.79 | ESR1 (0.48) | ESR1ESRRGMEN1KMT2AKDM4E | |
| SCHEMBL10484167 | 0.79 | ESR1 (0.48) | ESR1ESRRGMEN1KMT2AKDM4E | |
| SCHEMBL10484230 | 0.79 | PSMB1 (0.61) | ESR1ESRRGMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806685-A | EXERTS VARIOUS EFFECTS ON ENDOCRINOUS SYSTEM OF RATS; INHIBITS GROWTH OF MAMMARY TUMORS | GYOGYSZERKUTATO INTEEZET/PHARMACEUTICAL RESEARCH INSTITUTE (HU) | 1989-02-21 | — | — | US | disclosed |