Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660266 | 0.98 | ALDH1A1 (0.54) | HPRT1ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL10484087 | 0.92 | HPRT1 (0.56) | HPRT1ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL31081866 | 0.88 | ALDH1A1 (0.56) | HPRT1ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL9609738 | 0.88 | ALDH1A1 (0.56) | HPRT1ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL7638103 | 0.85 | TOP2A (0.40) | HPRT1ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL2310522 | 0.85 | HPRT1 (0.52) | HPRT1ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL18074888 | 0.84 | NR4A1 (0.56) | ALDH1A1HSD17B10AKR1B1TSHRTDP1 | |
| SCHEMBL2310621 | 0.82 | ALDH1A1 (0.50) | HPRT1ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL30975095 | 0.81 | CYP1A2 (0.60) | CYP2A6TSHRCYP1A2 | |
| SCHEMBL8374388 | 0.81 | TSHR (0.48) | HPRT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8963128-B2 | Compound for organic thin film transistor and organic thin film transistor using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20110180790-A1 | COMPOUND FOR ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM TRANSISTOR USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-07-28 | — | — | US | disclosed |
| US-4829090-A | SECONDARY AMINES, ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1989-05-09 | — | — | US | disclosed |
| US-4810727-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0125701-B1 | POLYCYCLIC AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-08-03 | — | — | EP | disclosed |
| US-4719048-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719046-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0125701-A2 | Polycyclic aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110180790-A1 | COMPOUND FOR ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM TRANSISTOR USING THE SAME | TCF4, CDH1, RCOR1 | HPRT1 275/4885ALDH1A1 1655/4885HSD17B10 2579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.