Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10529330 | 0.88 | MCL1 (0.43) | MCL1GRM2GRM3MTNR1ACOPS5 | |
| SCHEMBL10484234 | 0.79 | MCL1 (0.46) | MCL1GRM2GRM3MTNR1ATDP1 | |
| SCHEMBL10484353 | 0.79 | MTNR1A (0.45) | MCL1GRM2GRM3MTNR1ATDP1 | |
| SCHEMBL9613811 | 0.77 | KDM4E (0.50) | MCL1TDP1KMT2A | |
| SCHEMBL10484268 | 0.74 | MCL1 (0.35) | MCL1MEN1KMT2A | |
| SCHEMBL10484243 | 0.73 | GRM2 (0.43) | MCL1GRM2GRM3MTNR1ATDP1 | |
| SCHEMBL10484301 | 0.73 | GRM2 (0.43) | MCL1GRM2GRM3MTNR1ATDP1 | |
| SCHEMBL10531949 | 0.71 | MCL1 (0.42) | MCL1GRM2GRM3MTNR1ATDP1 | |
| SCHEMBL10484232 | 0.71 | MTNR1A (0.42) | MCL1GRM2GRM3MTNR1ATDP1 | |
| SCHEMBL2314388 | 0.70 | MEN1 (0.66) | MCL1MTNR1ATDP1CYP1A2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876282-A | ANTIDEPRESSANT, DIETETICS, ANTIALCOHOLISM AGENT | ELI LILLY AND COMPANY (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0318234-A2 | Improvements in or relating to selective serotonin uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |