Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484234 | 0.93 | MCL1 (0.46) | GRM2GRM3TDP1KDM4EMTNR1A | |
| SCHEMBL10530397 | 0.90 | MEN1 (0.40) | GRM2GRM3TDP1KDM4EMTNR1A | |
| SCHEMBL10531949 | 0.82 | MCL1 (0.42) | GRM2GRM3TDP1KDM4EMTNR1A | |
| SCHEMBL10527929 | 0.81 | KDM4E (0.41) | GRM2GRM3TDP1KDM4EMTNR1A | |
| SCHEMBL9614076 | 0.81 | HTR1B (0.49) | TDP1KDM4EMCL1KMT2AALDH1A1 | |
| SCHEMBL10484346 | 0.73 | MCL1 (0.48) | GRM2GRM3TDP1MTNR1AMCL1 | |
| SCHEMBL10484353 | 0.73 | MTNR1A (0.45) | GRM2GRM3TDP1KDM4EMTNR1A | |
| SCHEMBL9613987 | 0.73 | HTR1B (0.46) | TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL9613816 | 0.73 | HTR1B (0.46) | TDP1KDM4EMCL1KMT2AALDH1A1 | |
| SCHEMBL9613801 | 0.72 | HTR1B (0.45) | TDP1KDM4EMCL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876282-A | ANTIDEPRESSANT, DIETETICS, ANTIALCOHOLISM AGENT | ELI LILLY AND COMPANY (US) | 1989-10-24 | — | — | US | claimed |
| US-4876282-A | ANTIDEPRESSANT, DIETETICS, ANTIALCOHOLISM AGENT | ELI LILLY AND COMPANY (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0318234-A2 | Improvements in or relating to selective serotonin uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |