Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634061 | 0.90 | TDP1 (0.51) | TCF4CTNNB1GAACYP2C9TDP1 | |
| SCHEMBL7733944 | 0.90 | TDP1 (0.51) | TCF4CTNNB1GAACYP2C9TDP1 | |
| SCHEMBL3137310 | 0.89 | TSHR (0.45) | TCF4CTNNB1GAATSHRPTGS2 | |
| SCHEMBL10484394 | 0.85 | TSHR (0.45) | GAATSHRPTGS2MAPTALDH1A1 | |
| SCHEMBL10484503 | 0.85 | TSHR (0.45) | GAATSHRPTGS2MAPTALDH1A1 | |
| SCHEMBL10484442 | 0.84 | TDP1 (0.57) | TCF4CTNNB1GAACYP2C9TDP1 | |
| SCHEMBL128521 | 0.81 | CA12 (0.44) | GAACYP2C9TDP1MAPTALDH1A1 | |
| SCHEMBL9634065 | 0.80 | CA12 (0.41) | GAACYP2C9TSHRPTGS2ALDH1A1 | |
| Tetraphenylphosphonium SCHEMBL6735186 | 0.79 | TSHR (0.46) | TCF4CTNNB1GAATSHRPTGS2 | |
| SCHEMBL10484434 | 0.78 | TDP1 (0.49) | TCF4CTNNB1GAACYP2C9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496643-A | PHOSPHONIUM, ARSONIUM, OR STIBONIUM COMPOUND IN BINDER AS TONER AND FLUOROCARBON CARRIER COATED PARTICLES | EASTMAN KODAK COMPANY (US) | 1985-01-29 | — | — | US | claimed |
| US-4855396-A | BINDER/CHARGE AGENT IN ELECTROSTATOGRAPHIC TONER PARTICLES | EASTMAN KODAK COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4837394-A | CHARGE CONTROL AGENTS | EASTMAN KODAK COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0161128-A1 | Two-component dry electrostatic developer composition | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-11-13 | — | — | EP | disclosed |