SCHEMBL3137310

SCHEMBL3137310

COC(=O)c1cc(C(=O)OC)cc(S(=O)(=O)[O-])c1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
PTGS2 P35354 1/20 0.43
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 2/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
LMNA P02545 1/20 0.42
FBP1 P09467 1/20 0.40
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 2/20 0.39
PPARA Q07869 1/20 0.39
KMT2A Q03164 1/20 0.39
POLB P06746 2/20 0.39
TCF4 P15884 1/20 0.39
CTNNB1 P35222 1/20 0.39
ACLY P53396 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10484394 0.96 TSHR (0.45) TSHRPTGS2KDM4EALDH1A1HPGD
SCHEMBL10484503 0.96 TSHR (0.45) TSHRPTGS2KDM4EALDH1A1HPGD
Tetraphenylphosphonium SCHEMBL6735186 0.90 TSHR (0.46) TSHRPTGS2KDM4EALDH1A1HPGD
SCHEMBL10484459 0.89 TCF4 (0.45) TSHRPTGS2KDM4EALDH1A1HPGD
SCHEMBL6735230 0.85 LMNA (0.44) TSHRPTGS2KDM4EALDH1A1HPGD
SCHEMBL9556912 0.85 CA12 (0.46) KDM4EALDH1A1HPGDGAALMNA
SCHEMBL6729402 0.83 HPGD (0.43) TSHRPTGS2KDM4EALDH1A1HPGD
SCHEMBL2769023 0.83 TSHR (0.43) TSHRPTGS2KDM4EALDH1A1HPGD
SCHEMBL9634065 0.83 CA12 (0.41) TSHRPTGS2KDM4EALDH1A1HPGD
SCHEMBL6394369 0.83 TSHR (0.47) TSHRPTGS2KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7641819-B2 Biasable transfer composition and member EASTMAN KODAK COMPANY (US) 2010-01-05 US disclosed
US-20070075295-A1 Biasable transfer composition and member EASTMAN KODAK COMPANY 2007-04-05 US disclosed
US-4855396-A BINDER/CHARGE AGENT IN ELECTROSTATOGRAPHIC TONER PARTICLES EASTMAN KODAK COMPANY (US) 1989-08-08 US disclosed
US-4837393-A Electrostatographic toner particle comprising a polyester containing a covalently bound quaternary phosphonium salt EASTMAN KODAK COMPANY (US) 1989-06-06 US disclosed
US-4837394-A CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1989-06-06 US disclosed
US-4035346-A ANTISTATIC E. I. DU PONT DE NEMOURS AND CO. (US) 1977-07-12 US disclosed
US-4006123-A Conductive aliphatic polyester or polyetherester having units containing phosphonium sulfonate groups E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-02-01 US disclosed