Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TCF4 | P15884 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634061 | 1.00 | TDP1 (0.51) | TDP1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL10484442 | 0.95 | TDP1 (0.57) | TDP1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL10484459 | 0.90 | TCF4 (0.45) | TDP1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL10484434 | 0.88 | TDP1 (0.49) | TDP1MAPTTSHRKMT2ACYP2C9 | |
| SCHEMBL10484503 | 0.87 | TSHR (0.45) | MAPTTSHRFBP1ALDH1A1CA12 | |
| SCHEMBL10484394 | 0.87 | TSHR (0.45) | MAPTTSHRFBP1ALDH1A1CA12 | |
| SCHEMBL11051887 | 0.86 | TDP1 (0.48) | TDP1MAPTTSHRKMT2ACYP2C9 | |
| SCHEMBL9634065 | 0.84 | CA12 (0.41) | TSHRCYP2C9FBP1ALDH1A1CA12 | |
| SCHEMBL128521 | 0.83 | CA12 (0.44) | TDP1MAPTKMT2AMEN1CYP2C9 | |
| SCHEMBL10484476 | 0.83 | KMT2A (0.47) | TDP1MAPTKMT2ACYP2C9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161128-B1 | TWO-COMPONENT DRY ELECTROSTATIC DEVELOPER COMPOSITION | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-02-08 | — | — | EP | claimed |
| US-4496643-A | PHOSPHONIUM, ARSONIUM, OR STIBONIUM COMPOUND IN BINDER AS TONER AND FLUOROCARBON CARRIER COATED PARTICLES | EASTMAN KODAK COMPANY (US) | 1985-01-29 | — | — | US | claimed |
| US-6416921-B1 | FORMING NON-SPHERICAL TONER PARTICLES USING LIMITED COALESCENSE; IMPROVED TRANSFER AND CLEANING EFFICIENCY | HEIDELBERG DIGITAL L.L.C. | 2002-07-09 | — | — | US | disclosed |
| US-4855396-A | BINDER/CHARGE AGENT IN ELECTROSTATOGRAPHIC TONER PARTICLES | EASTMAN KODAK COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4837394-A | CHARGE CONTROL AGENTS | EASTMAN KODAK COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0161128-B1 | TWO-COMPONENT DRY ELECTROSTATIC DEVELOPER COMPOSITION | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-02-08 | — | — | EP | disclosed |
| EP-0161128-A1 | Two-component dry electrostatic developer composition | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-11-13 | — | — | EP | disclosed |
| US-4496643-A | PHOSPHONIUM, ARSONIUM, OR STIBONIUM COMPOUND IN BINDER AS TONER AND FLUOROCARBON CARRIER COATED PARTICLES | EASTMAN KODAK COMPANY (US) | 1985-01-29 | — | — | US | disclosed |