SCHEMBL9634065

SCHEMBL9634065

COC(=O)c1ccc([P+](C)(c2ccccc2)c2ccccc2)cc1.Cc1ccc(S(=O)(=O)[O-])cc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
CA14 Q9ULX7 3/20 0.41
EGFR P00533 1/20 0.41
CYP2C9 P11712 5/20 0.40
TSHR P16473 2/20 0.40
POLB P06746 2/20 0.40
PTGS2 P35354 1/20 0.40
FBP1 P09467 1/20 0.40
ALDH1A1 P00352 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
LMNA P02545 1/20 0.38
PLAU P00749 1/20 0.38
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10484503 0.87 TSHR (0.45) CA12CA1CA2CA9CA14
SCHEMBL10484394 0.87 TSHR (0.45) CA12CA1CA2CA9CA14
SCHEMBL9635307 0.87 LMNA (0.46) POLBALDH1A1GAALMNAHTT
SCHEMBL9634057 0.85 GAA (0.45) POLBALDH1A1KDM4EGAAPKM
SCHEMBL7733944 0.84 TDP1 (0.51) CA12CA1CA2CA9CA14
SCHEMBL9634061 0.84 TDP1 (0.51) CA12CA1CA2CA9CA14
SCHEMBL3137310 0.83 TSHR (0.45) CA12CA1CA2CA9CA14
SCHEMBL9634073 0.82 MAPT (0.43) POLBPTGS2ALDH1A1KDM4EGAA
SCHEMBL10484459 0.80 TCF4 (0.45) CYP2C9TSHRPOLBPTGS2ALDH1A1
SCHEMBL8373609 0.80 PTGS2 (0.42) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315082-B1 PROCESS FOR INCREASING THE ELECTROSTATIC CHARGEABILITY OF POWDER PAINTS OR POWDERS AND THEIR USE IN THE SURFACE COATING OF SOLID ITEMS HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-06 EP disclosed
EP-0315082-A2 Process for increasing the electrostatic chargeability of powder paints or powders and their use in the surface coating of solid items HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-10 EP disclosed