Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430482 | 0.82 | CXCR4 (0.40) | CXCR4CA12CA9CA3CA4 | |
| SCHEMBL9528787 | 0.78 | CA1 (0.40) | CXCR4CA12CA9CA1CA2 | |
| SCHEMBL9528515 | 0.78 | CA9 (0.43) | CXCR4CA12CA9CA3CA4 | |
| Hydrochloric Acid SCHEMBL7860781 | 0.77 | KMT2A (0.52) | CDK1ALDH1A1RECQLCCNA2CDK2 | |
| SCHEMBL17577086 | 0.76 | CA1 (0.39) | CXCR4CA12CA9CA1CA2 | |
| SCHEMBL11219384 | 0.74 | HRH4 (0.41) | NPY1RNPY5RCXCR4BRAFPDE4A | |
| SCHEMBL18062209 | 0.74 | CA1 (0.41) | CXCR4CA12CA9CA1CA2 | |
| SCHEMBL3265896 | 0.73 | LMNA (0.50) | CA9ALDH1A1CA1CA2 | |
| SCHEMBL21527302 | 0.73 | CA12 (0.49) | NPY1RNPY5RCXCR4NPC1MITF | |
| SCHEMBL14621844 | 0.73 | P2RX3 (0.37) | P2RX3P2RX2CDK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4838893-A | AND TETRAAMINOPYRIDINES ASDEVELOPER COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-06-13 | — | — | US | disclosed |
| US-4684371-A | Oxidation hair dyes comprising m-phenylenediamine derivatives as coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1987-08-04 | — | — | US | disclosed |
| US-4552565-A | Hair dyes: diresorcyl sulphide, sulphoxide or sulphone coupling agents | HENKEL KGAA (DE) | 1985-11-12 | — | — | US | disclosed |
| US-4371370-A | Oxidation hair dyes comprising bis-(2,4-diaminophenoxy)-alkanols as coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1983-02-01 | — | — | US | disclosed |
| US-4325704-A | CONTAINING A DEVELOPER AND AN N-BENZYL-M-PHENYLENEDIAMINE DERIVATIVE AS A COUPLER | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4322212-A | AS COUPLERS WITH CONVENTIONAL DEVELOPERS IN AQUEOUS SOLUTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-03-30 | — | — | US | disclosed |
| US-4213758-A | Oxidation hair dyes based upon tetraaminopyrimidine developers and couplers therefor | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-07-22 | — | — | US | disclosed |
| US-RE30199-E | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-01-29 | — | — | US | disclosed |
| US-4171203-A | IN COMBINATION WITH A TETRAAMINOPYRIMIDING COUPLER SURFACTANTS AND THICKENERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-10-16 | — | — | US | disclosed |
| US-4168953-A | Oxidation hair dyes based upon tetraaminopyrimidine developers and monohydroxyindazole couplers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1979-09-25 | — | — | US | disclosed |
| US-4129413-A | Oxidation hair dyes based upon tetraaminopyrimidine developers and mono- and dialkyl -m- dihydroxy benzene couplers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1978-12-12 | — | — | US | disclosed |
| US-4003699-A | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL & CIE G.M.B.H. (DT) | 1977-01-18 | — | — | US | disclosed |