SCHEMBL11219384

SCHEMBL11219384

NCCNc1nc(N)cc(N)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 5/20 0.41
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CXCR4 P61073 1/20 0.38
NPY1R P25929 1/20 0.36
NPY5R Q15761 1/20 0.36
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
CA12 O43570 1/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
SYK P43405 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL430482 0.80 CXCR4 (0.40) TDP1CXCR4MEN1GAAMAPK1
SCHEMBL9528515 0.76 CA9 (0.43) CXCR4CA12CA3CA4CA6
SCHEMBL9528787 0.76 CA1 (0.40) CXCR4CA12CA9
SCHEMBL11216579 0.76 KMT2A (0.38) CXCR4MEN1GAAMAPK1KMT2A
SCHEMBL7204411 0.75 CXCR4 (0.55) HRH4CXCR4SYKALDH1A1
SCHEMBL10485477 0.74 NPY1R (0.36) CXCR4NPY1RNPY5RCA12CA3
SCHEMBL17577086 0.74 CA1 (0.39) HRH4CXCR4CA12CA9
SCHEMBL25086773 0.74 DNM2 (0.36) HRH4MAPTNPY1RNPY5RMEN1
SCHEMBL4221010 0.74 NPY1R (0.38) HRH4CXCR4NPY1RNPY5RPRKCH
SCHEMBL18062209 0.73 CA1 (0.41) CXCR4CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0083765-A2 Reactive dyes BASF Aktiengesellschaft (DE) 1983-07-20 EP disclosed