SCHEMBL10485643

SCHEMBL10485643

CCCc1nc2nc(-c3ccccc3)cc(O)n2n1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 14/20 0.52
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
GAA P10253 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
CTSK P43235 1/20 0.44
ATM Q13315 1/20 0.44
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408728 0.89 KDM4E (0.45) PDE10AKDM4EALDH1A1HPGDGAA
SCHEMBL11582826 0.85 PDE10A (0.46) PDE10AKDM4EALDH1A1HPGDGAA
SCHEMBL10407886 0.82 TSHR (0.55) PDE10AKDM4EALDH1A1HPGDGAA
SCHEMBL5200396 0.80 KDM4E (0.46) PDE10AKDM4EALDH1A1HPGDGAA
SCHEMBL5143556 0.78 ALDH1A1 (0.44) KDM4EALDH1A1HPGDGAACYP1A2
SCHEMBL14510132 0.76 PDE10A (0.43) PDE10AKDM4EALDH1A1HPGDCYP2C9
SCHEMBL9173148 0.74 RECQL (0.40) PDE10AKDM4EALDH1A1HTT
SCHEMBL259589 0.69 PDE10A (1.00) PDE10A
SCHEMBL5146982 0.68 KDM4E (0.69) KDM4EALDH1A1HPGDGAACYP1A2
SCHEMBL5145693 0.68 UBE2M (0.42) KDM4EALDH1A1HPGDGAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4871653-A DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US disclosed
US-4840879-A COLORED LATENT IMAGE IS REACTION PRODUCT OF COUPLER AND AROMATIC PRIMARY AMINO COLOR DEVELOPER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-20 US disclosed
EP-0089101-A2 Direct positive image-forming process KONICA CORPORATION (JP) 1983-09-21 EP disclosed