SCHEMBL5145693

SCHEMBL5145693

Oc1cc(-c2ccccc2)nc2nnnn12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UBE2M P61081 3/20 0.42
DCUN1D1 Q96GG9 3/20 0.42
SMN1; SMN2 Q16637 7/20 0.42
ALDH1A1 P00352 6/20 0.42
KDM4E B2RXH2 4/20 0.42
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
NTSR1 P30989 1/20 0.41
CGAS Q8N884 1/20 0.40
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
MAPK10 P53779 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HPGD P15428 4/20 0.39
TP53 P04637 3/20 0.39
POLB P06746 1/20 0.38
ADORA2A P29274 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18496479 0.81 KDM4E (0.46) UBE2MDCUN1D1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL5143556 0.75 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1
SCHEMBL5200396 0.74 KDM4E (0.46) SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1
SCHEMBL5146982 0.74 KDM4E (0.69) UBE2MDCUN1D1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL5199036 0.71 MAPT (0.51) SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1
SCHEMBL11582826 0.71 PDE10A (0.46) SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1
SCHEMBL5155815 0.70 HSD17B10 (0.50) SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1
SCHEMBL10408728 0.70 KDM4E (0.45) ALDH1A1KDM4ELMNACYP1A2CYP2C9
SCHEMBL9452026 0.69 MEN1 (0.44) SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1
SCHEMBL29152863 0.69 RAD52 (0.49) SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220143035-A1 METHODS FOR TREATING AUTOIMMUNE OR AUTOINFLAMMATORY DISEASE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-05-12 US disclosed
US-7906038-B2 Aqueous polishing liquid and chemical mechanical polishing method FUJIFILM CORPORATION (JP) 2011-03-15 US disclosed
US-7906038-B2 Aqueous polishing liquid and chemical mechanical polishing method FUJIFILM CORPORATION (JP) 2011-03-15 US disclosed
US-7857985-B2 Metal-polishing liquid and chemical mechanical polishing method using the same FUJIFILM CORPORATION (JP) 2010-12-28 US disclosed
US-7857985-B2 Metal-polishing liquid and chemical mechanical polishing method using the same FUJIFILM CORPORATION (JP) 2010-12-28 US disclosed
US-7547335-B2 Metal polishing composition and method of polishing using the same FUJIFILM CORPORATION (JP) 2009-06-16 US disclosed
US-7547335-B2 Metal polishing composition and method of polishing using the same FUJIFILM CORPORATION (JP) 2009-06-16 US disclosed
US-20070287362-A1 POLISHING COMPOSITION AND METHOD OF POLISHING WITH THE SAME FUJIFILM CORPORATION 2007-12-13 US disclosed
US-20070287362-A1 POLISHING COMPOSITION AND METHOD OF POLISHING WITH THE SAME FUJIFILM CORPORATION 2007-12-13 US disclosed
US-20070236764-A1 SILVER HALIDE HOLOGRAHIC SENSITIVE MATERIAL AND SYSTEM FOR TAKING HOLOGRAHIC IMAGES BY USING THE SAME FUJIFILM CORPORATION 2007-10-11 US disclosed
US-20070186484-A1 Metal-polishing liquid and chemical mechanical polishing method using the same FUJIFILM CORPORATION (JP) 2007-08-16 US disclosed
US-20070186484-A1 Metal-polishing liquid and chemical mechanical polishing method using the same FUJIFILM CORPORATION (JP) 2007-08-16 US disclosed
US-7241564-B2 Silver halide holographic sensitive material and system for taking holographic images by using the same FUJIFILM CORPORATION (JP) 2007-07-10 US disclosed
EP-1798608-A1 Hologram production method and hologram production system employing silver halide photosensitive material Fujifilm Corporation (JP) 2007-06-20 EP disclosed
US-20070134559-A1 Hologram production method and hologram production system employing silver halide photosensitive material FUJIFILM CORPORATION (JP) 2007-06-14 US disclosed
US-20070069176-A1 Aqueous polishing liquid and chemical mechanical polishing method FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070069176-A1 Aqueous polishing liquid and chemical mechanical polishing method FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
EP-1624337-A2 Silver halide holographic sensitive material and system for taking holographic images by using the same Fuji Photo Film Co., Ltd. (JP) 2006-02-08 EP disclosed
US-20060024626-A1 Silver halide holographic sensitive material and system for taking holographic images by using the same FUJI PHOTO FILM CO., LTD. 2006-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143035-A1 METHODS FOR TREATING AUTOIMMUNE OR AUTOINFLAMMATORY DISEASE HSPA8, HSPBP1, HSP90AB1 UBE2M 2786/4885DCUN1D1 2973/4885SMN1; SMN2 3964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.