Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10485939 | 0.98 | FFAR1 (0.49) | FFAR1ALDH1A1BLMKEAP1NPSR1 | |
| SCHEMBL10485933 | 0.86 | BLM (0.47) | FFAR1ALDH1A1BLMTHRATHRB | |
| SCHEMBL10485710 | 0.84 | ANPEP (0.46) | FFAR1ALDH1A1BLMTHRATHRB | |
| SCHEMBL10601735 | 0.83 | GRIN2D (0.52) | ALDH1A1BLMLMNAGRIN2DGRIN2A | |
| SCHEMBL10485816 | 0.83 | GRIN2D (0.52) | ALDH1A1BLMLMNAGRIN2DGRIN2A | |
| SCHEMBL104462 | 0.81 | FFAR1 (0.59) | FFAR1ALDH1A1KEAP1NPSR1THRA | |
| SCHEMBL10485692 | 0.81 | GRIN2D (0.54) | ALDH1A1BLMLMNAGRIN2DGRIN2A | |
| SCHEMBL10485950 | 0.81 | FFAR1 (0.46) | FFAR1BLMLMNA | |
| SCHEMBL664336 | 0.79 | FFAR1 (0.61) | FFAR1ALDH1A1BLMKEAP1NPSR1 | |
| SCHEMBL9546062 | 0.79 | FFAR1 (0.47) | FFAR1BLMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | claimed |
| EP-0194693-A1 | Polyprenyl compounds, processes for preparing them, and pharmaceutical composition containing them | Eisai Co., Ltd. (JP) | 1986-09-17 | — | — | EP | claimed |
| US-4883916-A | ANTICHOLESTEROL, ANTIARTERIOSCELEROSIS | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | disclosed |
| US-4788330-A | Polyprenyl compounds | EISAI CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0194693-A1 | Polyprenyl compounds, processes for preparing them, and pharmaceutical composition containing them | Eisai Co., Ltd. (JP) | 1986-09-17 | — | — | EP | disclosed |