SCHEMBL664336

SCHEMBL664336

CC(C)Cc1ccc(CCC(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.61
KEAP1 Q14145 1/20 0.59
PTGS1 P23219 3/20 0.58
PTGS2 P35354 3/20 0.58
LMNA P02545 2/20 0.58
CYP2C9 P11712 2/20 0.58
AKR1C3 P42330 2/20 0.58
CXCR1 P25024 2/20 0.58
CXCR2 P25025 2/20 0.58
ALB P02768 1/20 0.58
ESR1 P03372 1/20 0.58
ALOX5 P09917 1/20 0.58
RARB P10826 1/20 0.58
ADRB3 P13945 1/20 0.58
NFKB1 P19838 1/20 0.58
HTR2A P28223 1/20 0.58
NR1I3 Q14994 1/20 0.58
SLC22A6 Q4U2R8 1/20 0.58
CXCL8 P10145 1/20 0.58
TSHR P16473 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9330654 0.98 FFAR1 (0.59) FFAR1KEAP1PTGS1PTGS2LMNA
SCHEMBL25146556 0.94 FFAR1 (0.67) FFAR1KEAP1PTGS1PTGS2LMNA
SCHEMBL765464 0.90 HSD17B10 (0.61) FFAR1KEAP1PTGS1PTGS2LMNA
SCHEMBL8959741 0.89 MAPT (0.59) FFAR1PTGS1PTGS2LMNACYP2C9
SCHEMBL27824740 0.88 PTGS1 (0.53) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL764976 0.87 MAPT (0.62) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL10442968 0.86 PTGS1 (0.53) FFAR1KEAP1PTGS1PTGS2LMNA
SCHEMBL5196414 0.86 ALDH1A1 (0.59) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL104462 0.86 FFAR1 (0.59) FFAR1KEAP1LMNAALDH1A1NPSR1
SCHEMBL25146537 0.86 FFAR1 (0.56) FFAR1PTGS1PTGS2LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 513 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119493348-A Photoresist stripping liquid and preparation method and application thereof 福建泓光半导体材料有限公司 2025-02-21 CN claimed
CN-114195633-A Synthesis method of ibuprofen impurity F 浙江新和成股份有限公司 2022-03-18 CN claimed
CN-108181407-B Method for detecting impurity F in ibuprofen raw material 扬子江药业集团南京海陵药业有限公司 2021-01-19 CN claimed
US-20160231323-A1 PROTECTION OF TCR SIGNALING CHAINS IN CANCER PATIENTS AND ENHANCEMENT OF CAR-T CELL THERAPY Batu Biologics, Inc. (US) 2016-08-11 US claimed
US-20140030323-A1 CONTROLLED RELEASE OF N-ACETYLCYSTEINE (NAC) FOR REDUCTION OF SYSTEMIC AND/OR VASCULAR INFLAMMATION TIARA PHARMACEUTICALS, INC. (US) 2014-01-30 US claimed
CN-102716069-A Injection liquid containing ibuprofen and preparation process of injection liquid WUXI KFT PHARMACEUTICAL TECHNOLOGY CO LTD 2012-10-10 CN claimed
US-20120046232-A1 COMPOSITIONS AND METHODS FOR REDUCING RELAPSE OF ADDICTIVE BEHAVIOR MEDICAL UNIVERSITY OF SOUTH CAROLINA 2012-02-23 US claimed
US-20110244045-A1 CONTROLLED RELEASE OF N-ACETYLCYSTEINE (NAC) FOR REDUCTION OF SYSTEMIC AND/OR VASCULAR INFLAMMATION TIARA PHARMACEUTICALS ,INC. (US) 2011-10-06 US claimed
EP-1898930-A2 TREATMENT OF INFLAMMATORY CONDITIONS Dynamis Therapeutics, Inc. (US) 2008-03-19 EP claimed
WO-2006138609-A2 TREATMENT OF INFLAMMATORY CONDITIONS DYNAMIS THERAPEUTICS, INC. (US) 2006-12-28 WO claimed
US-6416772-B1 Topical dermal anaesthetic PATTERSON, RICHARD 2002-07-09 US claimed
EP-0253083-B1 Topical vaginal use of lysine p-isobutylphenylpropionate in antiinflammatory treatment LISAPHARMA SPA (IT) 1994-08-31 EP claimed
EP-0374850-B1 Method for preparing alpha-(4-isobutylphenyl)propionic acid or its precursor NIPPON PETROCHEMICALS CO LTD (JP) 1994-03-09 EP claimed
EP-0194693-B1 POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM Eisai Co., Ltd. (JP) 1989-07-26 EP claimed
EP-0194693-A1 Polyprenyl compounds, processes for preparing them, and pharmaceutical composition containing them Eisai Co., Ltd. (JP) 1986-09-17 EP claimed
EP-0052909-B1 DERIVATIVE OF ALFA-MERCAPTOPROPIONILGLICINE HAVING THERAPEUTICAL ACTIVITY, PROCESS FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS Real S.a.s. di Alberto Reiner & C. (IT) 1985-04-10 EP claimed
EP-0052910-B1 DERIVATIVE OF N-ACETILCYSTEINE HAVING THERAPEUTICAL ACTIVITY, PROCESS FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS Real S.a.s. di Alberto Reiner & C. (IT) 1985-04-10 EP claimed
US-4341798-A ANTIINFLAMMATORY AGENT LABORATORI PROPHIN S.P.A. (IT) 1982-07-27 US claimed
EP-0052910-A1 Derivative of N-acetilcysteine having therapeutical activity, process for its preparation and related pharmaceutical compositions Real S.a.s. di Alberto Reiner & C. (IT) 1982-06-02 EP claimed
EP-0052909-A1 Derivative of alfa-mercaptopropionilglicine having therapeutical activity, process for its preparation and related pharmaceutical compositions Real S.a.s. di Alberto Reiner & C. (IT) 1982-06-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140030323-A1 CONTROLLED RELEASE OF N-ACETYLCYSTEINE (NAC) FOR REDUCTION OF SYSTEMIC AND/OR VASCULAR INFLAMMATION IL6, IL1B, NACA FFAR1 962/4885KEAP1 559/4885PTGS1 28/4885
US-20120046232-A1 COMPOSITIONS AND METHODS FOR REDUCING RELAPSE OF ADDICTIVE BEHAVIOR GRM6, GRM5, GRM7 FFAR1 1932/4885KEAP1 1217/4885PTGS1 1096/4885
US-20110244045-A1 CONTROLLED RELEASE OF N-ACETYLCYSTEINE (NAC) FOR REDUCTION OF SYSTEMIC AND/OR VASCULAR INFLAMMATION IL6, IL1B, NACA FFAR1 962/4885KEAP1 559/4885PTGS1 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.