Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10485950 | 0.99 | FFAR1 (0.46) | FFAR1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL10486233 | 0.87 | FAAH (0.40) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL10602088 | 0.87 | FFAR1 (0.46) | FFAR1LMNABLMACHEITGB1 | |
| SCHEMBL5572746 | 0.82 | PTGS1 (0.62) | FFAR1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL3972122 | 0.82 | PTGS1 (0.62) | FFAR1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL10485710 | 0.81 | ANPEP (0.46) | FFAR1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL9546047 | 0.80 | POLB (0.44) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL10485939 | 0.80 | FFAR1 (0.49) | FFAR1LMNABLM | |
| SCHEMBL10485933 | 0.80 | BLM (0.47) | FFAR1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL10485947 | 0.79 | OPRK1 (0.40) | PTGS1PTGS2LMNACYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337350-B1 | USE OF DIMETHYLHEPTYLPHENYL BUTANOYL ETHANOLAMINE IN TREATMENT OF HYPERURICEMIA | Eisai Co., Ltd. (JP) | 1993-07-07 | — | — | EP | disclosed |
| US-4883821-A | N-(3-(4'-(2\",6\"-DIMETHYLHEPTYL)PHENYL)BUTANOYL)-ETHANOLAMINE | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| US-4883916-A | ANTICHOLESTEROL, ANTIARTERIOSCELEROSIS | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| EP-0337350-A2 | Use of dimethylheptylphenyl butanoyl ethanolamine in treatment of hyperuricemia | Eisai Co., Ltd. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | disclosed |
| US-4788330-A | Polyprenyl compounds | EISAI CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0194693-A1 | Polyprenyl compounds, processes for preparing them, and pharmaceutical composition containing them | Eisai Co., Ltd. (JP) | 1986-09-17 | — | — | EP | disclosed |