Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566491 | 0.87 | DHFR (0.55) | DHFRSMN1; SMN2MAOBKDM4EALOX15 | |
| SCHEMBL9566557 | 0.80 | CYP1A2 (0.56) | DHFRSMN1; SMN2MAOBALDH1A1CYP1A2 | |
| SCHEMBL10486284 | 0.78 | SMN1; SMN2 (0.49) | DHFRSMN1; SMN2MAOBKDM4EALOX15 | |
| SCHEMBL3678540 | 0.75 | HSP90AA1 (0.58) | DHFRSMN1; SMN2KDM4EALOX15L3MBTL1 | |
| SCHEMBL9566443 | 0.75 | BRD4 (0.57) | DHFRSMN1; SMN2L3MBTL1 | |
| SCHEMBL8751778 | 0.74 | L3MBTL1 (0.47) | KDM4EALOX15L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL9566555 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EALOX15L3MBTL1ADORA2A | |
| Benzoguanamine SCHEMBL11620035 | 0.70 | ADORA2A (0.70) | DHFRSMN1; SMN2KDM4EALOX15L3MBTL1 | |
| SCHEMBL27612369 | 0.70 | DHFR (0.60) | DHFRMAOBADORA2AADORA1ALDH1A1 | |
| SCHEMBL30468191 | 0.70 | SMN1; SMN2 (0.71) | SMN1; SMN2KDM4EALOX15L3MBTL1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873242-A | NOOTROPIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-10 | — | — | US | claimed |
| US-4873242-A | NOOTROPIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-10 | — | — | US | disclosed |