Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 8/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10247441 | 0.86 | RARG (0.52) | SLC6A3SLC6A4CHRNB2CHRNA4RARG | |
| SCHEMBL10486022 | 0.83 | RARG (0.51) | RARGRARBKDM4EALDH1A1 | |
| SCHEMBL10486065 | 0.83 | SLC6A3 (0.47) | SLC6A3CYP11B1CYP11B2CYP19A1PLAU | |
| SCHEMBL10486405 | 0.83 | SLC6A3 (0.50) | SLC6A3CYP11B1CYP11B2CYP19A1PLAU | |
| SCHEMBL13900228 | 0.81 | CYP11B1 (0.69) | SLC6A3CYP11B1CYP11B2CYP19A1PLAU | |
| SCHEMBL10486277 | 0.81 | MAPK14 (0.45) | SLC6A3CHRNB2CHRNA4RARGRARB | |
| SCHEMBL10486068 | 0.78 | SLC6A3 (0.45) | SLC6A3CYP11B1CYP11B2CYP19A1PLAU | |
| SCHEMBL264087 | 0.76 | PTPN11 (0.51) | SLC6A3CYP11B1CYP11B2CYP19A1PLAU | |
| SCHEMBL69025 | 0.74 | PTPN11 (0.68) | CYP11B1CYP11B2CYP19A1PLAUPTPN11 | |
| SCHEMBL29365729 | 0.74 | PTPN11 (0.68) | CYP11B1CYP11B2CYP19A1PLAUPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810694-A | SKIN DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1989-03-07 | — | — | US | disclosed |