Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486289 | 0.84 | MAPK14 (0.43) | MAPK14CDK8ALOX15SLC6A3CHRNB2 | |
| SCHEMBL10486398 | 0.81 | SLC6A3 (0.53) | RARGSLC6A3RARBCHRNB2CHRNA4 | |
| SCHEMBL10486022 | 0.80 | RARG (0.51) | ALOX15RARGRARBKMT2AKDM4E | |
| SCHEMBL14157778 | 0.77 | HPGDS (0.55) | RAB9AKMT2AHPGDSCYP17A1CYP3A4 | |
| SCHEMBL22103835 | 0.71 | RARB (0.63) | ALOX15RARGRARBKMT2AKDM4E | |
| SCHEMBL29462817 | 0.71 | RARB (0.70) | ALOX15RARGRARBKMT2AKDM4E | |
| SCHEMBL20564812 | 0.71 | RARB (0.70) | ALOX15RARGRARBKMT2AKDM4E | |
| SCHEMBL3949393 | 0.71 | HDAC3 (0.62) | RAB9AKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL10486412 | 0.71 | RARG (0.44) | ALOX15RARGRARBKMT2AKDM4E | |
| SCHEMBL10486065 | 0.71 | SLC6A3 (0.47) | SLC6A3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810694-A | SKIN DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1989-03-07 | — | — | US | disclosed |