Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 8/20 | 0.44 |
| ▸ | PLAT | P00750 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486030 | 0.86 | RARG (0.41) | SLC6A3ALDH1A1SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL10486289 | 0.84 | MAPK14 (0.43) | SLC6A3ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL10486068 | 0.84 | SLC6A3 (0.45) | SLC6A3CYP11B1CYP11B2CYP19A1SLC6A4 | |
| SCHEMBL10486398 | 0.83 | SLC6A3 (0.53) | SLC6A3CYP11B1CYP11B2CYP19A1SLC6A4 | |
| SCHEMBL10486065 | 0.80 | SLC6A3 (0.47) | SLC6A3CYP11B1CYP11B2CYP19A1SLC6A4 | |
| SCHEMBL10247441 | 0.74 | RARG (0.52) | SLC6A3SLC6A4SLC6A2ALDH1A1ATM | |
| SCHEMBL13900228 | 0.72 | CYP11B1 (0.69) | SLC6A3CYP11B1CYP11B2CYP19A1SLC6A4 | |
| SCHEMBL10486417 | 0.72 | RXRA (0.42) | SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL16502622 | 0.71 | RBP4 (0.43) | SLC6A3SLC6A4SLC6A2PLAUALDH1A1 | |
| SCHEMBL16502580 | 0.71 | PDK2 (0.47) | SLC6A3SLC6A4SLC6A2PLAUALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810694-A | SKIN DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1989-03-07 | — | — | US | disclosed |