Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711866 | 0.94 | MCL1 (0.58) | CA1CA2PTGS2CA12CA7 | |
| SCHEMBL5313573 | 0.94 | HNF4A (0.53) | CA1CA2PTGS2CA12CA7 | |
| SCHEMBL15882918 | 0.87 | CA1 (0.71) | CA1CA2PTGS2CA12CA7 | |
| SCHEMBL330378 | 0.83 | KDM4E (0.67) | CA1CA2PTGS2CA12CA7 | |
| SCHEMBL30268239 | 0.83 | KDM4E (0.67) | CA1CA2PTGS2CA12CA7 | |
| SCHEMBL7706125 | 0.83 | ACMSD (0.49) | CA1CA2PTGS2CA12CA7 | |
| SCHEMBL7709289 | 0.83 | ACMSD (0.49) | CA1CA2PTGS2CA12CA7 | |
| SCHEMBL4454209 | 0.81 | HSD17B10 (0.59) | CA1CA2CA12CA7CA9 | |
| SCHEMBL11790065 | 0.81 | TDP1 (0.62) | CA1CA2PTGS2CA12CA7 | |
| SCHEMBL10541064 | 0.81 | KDM4E (0.64) | CA1CA2PTGS2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323773-A1 | METHODS AND MATERIALS FOR DETECTING MISFOLDED POLYPEPTIDES | Regents of the University of Minnesota (US) | 2024-02-21 | — | — | EP | claimed |
| WO-2022221683-A1 | METHODS AND MATERIALS FOR DETECTING MISFOLDED POLYPEPTIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-10-20 | — | — | WO | claimed |
| WO-2020242246-A1 | AMYLOID-BETA OLIGOMER DETECTION METHOD | 주식회사 캔티스 | 2020-12-03 | — | — | WO | claimed |
| US-20070224593-A1 | Diagnosis of transmissible spongiform encephalopathy | GOLDSTEIN LEE E | 2007-09-27 | — | — | US | claimed |
| US-20050227941-A1 | Sequestration of ass in the periphery in the absence of immunomodulating agent as a therapeutic approach for the treatment or prevention of beta-amyloid related diseases | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-10-13 | — | — | US | claimed |
| US-20250231165-A1 | DRUG PRODUCT SURROGATE SOLUTIONS | MODERNATX, INC. (US) | 2025-07-17 | — | — | US | disclosed |
| WO-2023069625-A1 | DRUG PRODUCT SURROGATE SOLUTIONS | MODERNATX, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| US-11125758-B2 | Methods and kits for detecting misfolded proteins | YALE UNIVERSITY (US) | 2021-09-21 | — | — | US | disclosed |
| US-20210255192-A1 | METHODS AND KITS FOR DETECTING MISFOLDED PROTEINS | YALE UNIVERSITY (US) | 2021-08-19 | — | — | US | disclosed |
| WO-2020242246-A1 | AMYLOID-BETA OLIGOMER DETECTION METHOD | 주식회사 캔티스 | 2020-12-03 | — | — | WO | disclosed |
| CN-110208540-A | The method and composition of preeclampsia detection and treatment | 耶鲁大学 | 2019-09-06 | — | — | CN | disclosed |
| CN-110187121-A | The method and composition of preeclampsia detection and treatment | 耶鲁大学 | 2019-08-30 | — | — | CN | disclosed |
| WO-2010062377-A2 | METHODS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF PREECLAMPSIA | YALE UNIVERSITY (US) | 2010-06-03 | — | — | WO | disclosed |
| WO-2009059239-A2 | REDUCING Aβ42 LEVELS AND Aβ AGGREGATION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20070224593-A1 | Diagnosis of transmissible spongiform encephalopathy | GOLDSTEIN LEE E | 2007-09-27 | — | — | US | disclosed |
| US-20050227941-A1 | Sequestration of ass in the periphery in the absence of immunomodulating agent as a therapeutic approach for the treatment or prevention of beta-amyloid related diseases | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-10-13 | — | — | US | disclosed |
| US-6417178-B1 | Amyloid binding nitrogen-linked compounds for the antemortem diagnosis of alzheimer's disease, in vivo imaging and prevention of amyloid deposits | UNIVERSITY OF PITTSBURGH | 2002-07-09 | — | — | US | disclosed |
| US-6168776-B1 | Alkyl, alkenyl and alkynyl Chrysamine G derivatives for the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition | UNIVERSITY OF PITTSBURGH | 2001-01-02 | — | — | US | disclosed |
| US-6133259-A | DIAGNOSIS OF ALZHEIMER'S DISEASE | UNIVERSITY OF PITTSBURGH (US) | 2000-10-17 | — | — | US | disclosed |
| US-6114175-A | AMYLOID-BINDING COMPOUNDS WHICH ARE NON-AZO DERIVATIVES OF CHRYSAMINE G TO DETERMINE DEGREE OF BRAIN DEPOSITS QUANTITATIVELY CHARACTERIZED BY AMYLOIDOSIS; DOWN'S SYNDROME; PREVENT CELL DEGENERATION; RADIOACTIVE IMAGING | UNIVERSITY OF PITTSBURGH (US) | 2000-09-05 | — | — | US | disclosed |